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1

Asparagine Synthetase Chemotherapy

Richards, Nigel G. J., Kilberg, Michael S.

Journal:

Annual Review of Biochemistry

Year:

2006

Language:

english

File:

PDF, 854 KB

english, 2006

2

Molecular Biology of Mammalian Amino Acid Transporters

Malandro, Marc S., Kilberg, Michael S.

Journal:

Annual Review of Biochemistry

Year:

1996

Language:

english

File:

PDF, 2.00 MB

english, 1996

3

Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element

Crawford, Rebecca R., Prescott, Eugenia T., Sylvester, Charity F., Higdon, Ashlee N., Shan, Jixiu, Kilberg, Michael S., Mungrue, Imran N.

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 3.34 MB

english, 2015

4

Response of placental amino acid transport to gestational age and intrauterine growth retardation

Matthews, James C., Beveridge, Mark J., Malandro, Marc S., Kilberg, Michael S., Novak, Donald A.

Journal:

Proceedings of The Nutrition Society

Year:

1998

Language:

english

File:

PDF, 882 KB

english, 1998

5

Induction of early growth response gene 1 (EGR1) by endoplasmic reticulum stress is mediated by the extracellular regulated kinase (ERK) arm of the MAPK pathways

Shan, Jixiu, Dudenhausen, Elizabeth, Kilberg, Michael S.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2018

Language:

english

File:

PDF, 4.64 MB

english, 2018

6

Protein Modification of Glutamine Transporters in SV40-Transformed Hepatocytes and Immunodetection of Proteins Associated with Hepatic System N Transport Activity

Tamarappoo, Balaji K., Singh, H. Paul, Kilberg, Michael S.

Journal:

Journal of Nutrition

Year:

1994

File:

PDF, 710 KB

1994

7

An Inhibitor of Human Asparagine Synthetase Suppresses Proliferation of an L-Asparaginase-Resistant Leukemia Cell Line

Jemy A. Gutierrez, Yuan-Xiang Pan, Lukasz Koroniak, Jun Hiratake, Michael S. Kilberg, Nigel G.J. Richards

Journal:

Chemistry & Biology

Year:

2006

Language:

english

File:

PDF, 266 KB

english, 2006

8

The Mechanism for Transcriptional Activation of the Human ATA2 Transporter Gene by Amino Acid Deprivation is Different than That for Asparagine Synthetase

Bain, Perry J., LeBlanc-Chaffin, Rene, Chen, Hong, Palii, Stela S., Leach, Kelly M., Kilberg, Michael S.

Journal:

Journal of Nutrition

Year:

2002

Language:

english

File:

PDF, 412 KB

english, 2002

9

Activity and protein localization of multiple glutamate transporters in gestation day 14 vs. day 20 rat placenta

Matthews, James C., Beveridge, Mark J., Malandro, Marc S., Rothstein, Jeffrey D., Campbell-Thompson, Martha, Verlander, Jill W., Kilberg, Michael S., Novak, Donald A.

Journal:

American journal of physiology. Cell physiology

Year:

1998

Language:

english

File:

PDF, 543 KB

english, 1998

10

Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization

LEUNG-PINEDA, Van, PAN, YuanXiang, CHEN, Hong, KILBERG, Michael S.

Journal:

Biochemical Journal

Year:

2004

Language:

english

File:

PDF, 416 KB

english, 2004

11

Amino acid transport in isolated rat hepatocytes

Michael S. Kilberg

Journal:

Journal of Membrane Biology

Year:

1982

Language:

english

File:

PDF, 1.24 MB

english, 1982

12

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Han, Jaeseok, Back, Sung Hoon, Hur, Junguk, Lin, Yu-Hsuan, Gildersleeve, Robert, Shan, Jixiu, Yuan, Celvie L., Krokowski, Dawid, Wang, Shiyu, Hatzoglou, Maria, Kilberg, Michael S., Sartor, Maureen A.,

Journal:

Nature Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.92 MB

english, 2013

13

Genetic potential and height velocity during childhood and adolescence do not fully account for shorter stature in cystic fibrosis

Zysman-Colman, Zofia N., Kilberg, Marissa J., Harrison, Victor S., Chesi, Alessandra, Grant, Struan F. A., Mitchell, Jonathan, Sheikh, Saba, Hadjiliadis, Denis, Rickels, Michael R., Rubenstein, Ronald

Journal:

Pediatric Research

Year:

2020

File:

PDF, 1.06 MB

2020

14

Substrate-dependent adaptive regulation and trans-inhibition of system A-mediated amino acid transport. Studies using rat hepatoma plasma membrane vesicles

Arnold D. Fong, Mary E. Handlogten, Michael S. Kilberg

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 785 KB

english, 1990

15

Hormonal Control of Amino Acid Transport in the Liver of Rats Exposed to Whole-Body γ Irradiation

Michael S. Kilberg and Otto W. Neuhaus

Journal:

Radiation Research

Year:

1978

Language:

english

File:

PDF, 495 KB

english, 1978

16

Encyclopedia of Life Sciences || Amino Acid Transporters

Kilberg, Michael S

Year:

2001

Language:

english

File:

PDF, 131 KB

english, 2001

17

Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway

Gjymishka, Altin, Su, Nan, Kilberg, Michael S.

Journal:

Biochemical Journal

Year:

2009

Language:

english

File:

PDF, 708 KB

english, 2009

18

[Methods in Enzymology] Biomembranes Part T Volume 173 || [37] Measurement of amino acid transport by hepatocytes in suspension or monolayer culture

Kilberg, Michael S.

Year:

1989

Language:

english

File:

PDF, 841 KB

english, 1989

19

MAPK signaling triggers transcriptional induction of cFOS during amino acid limitation of HepG2 cells

Shan, Jixiu, Donelan, William, Hayner, Jaclyn N., Zhang, Fan, Dudenhausen, Elizabeth E., Kilberg, Michael S.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

20

Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4–independent pathway

Nan Su, Michelle M. Thiaville, Keytam Awad, Altin Gjymishka, Jason O. Brant, Thomas P. Yang, Michael S. Kilberg

Journal:

Year:

2009

Language:

english

File:

PDF, 721 KB

english, 2009

21

Transport System A is not responsive to hormonal stimulation in primary cultures of fetal rat hepatocytes

Mary E. Handlogten, Michael S. Kilberg

Journal:

Biochemical and Biophysical Research Communications

Year:

1982

Language:

english

File:

PDF, 487 KB

english, 1982

22

Amino Acid Deprivation and Endoplasmic Reticulum Stress Induce Expression of Multiple Activating Transcription Factor-3 mRNA Species That, When Overexpressed in HepG2 Cells, Modulate Transcription by the Human Asparagine Synthetase Promoter

Pan, YuanXiang, Chen, Hong, Siu, Fai, Kilberg, Michael S.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 1.00 MB

english, 2003

23

[Methods in Enzymology] Branched-Chain Amino Acids Volume 166 || [32] Transport of branched-chain amino acids and their corresponding 2-keto acids by mammalian cells

Kilberg, Michael S.

Year:

1988

Language:

english

File:

PDF, 552 KB

english, 1988

24

Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation

Pan, Yuan-Xiang, Chen, Hong, Thiaville, Michelle M., Kilberg, Michael S.

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 310 KB

english, 2007

25

Regulation of the ATF3 gene by a single promoter in response to amino acid availability and endoplasmic reticulum stress in human primary hepatocytes and hepatoma cells

Hayner, Jaclyn N., Shan, Jixiu, Kilberg, Michael S.

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

26

Amino acid activation of amino acid transport system N early in primary cultures of rat hepatocytes

Lawrence Weissbach, Michael S. Kilberg

Journal:

Journal of Cellular Physiology

Year:

1984

Language:

english

File:

PDF, 710 KB

english, 1984

27

The regulation of neutral amino acid transport in mammalian cells

Mark A. Shotwell, Michael S. Kilberg, Dale L. Oxender

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes

Year:

1983

Language:

english

File:

PDF, 1.40 MB

english, 1983

28

Energization of amino acid transport in energy-depleted Ehrlich cells and plasma membrane vesicles

Motoyasu Ohsawa, Michael S. Kilberg, Gene Kimmel, Halvor N. Christensen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1980

Language:

english

File:

PDF, 1.06 MB

english, 1980

29

Adaptive regulation of neutral amino acid transport system A in rat H4 hepatoma cells

Michael S. Kilberg, He-Ping Han, Ellen F. Barber, Thomas C. Chiles

Journal:

Journal of Cellular Physiology

Year:

1985

Language:

english

File:

PDF, 889 KB

english, 1985

30

Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells

ASLANIAN, Ara M., KILBERG, Michael S.

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 282 KB

english, 2001

31

An Expression System for Mammalian Amino Acid Transporters Using a Stably Maintained Episomal Vector

James C. Matthews, Ara M. Aslanian, Kelly K. McDonald, Wenbo Yang, Marc S. Malandro, Donald A. Novak, Michael S. Kilberg

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 303 KB

english, 1997

32

Maintenance of glucagon-stimulated system A amino acid transport activity in rat liver plasma membrane vesicles

Mark A Schenerman, Michael S Kilberg

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1986

Language:

english

File:

PDF, 693 KB

english, 1986

33

ATF4-dependent transcription mediates signaling of amino acid limitation

Michael S. Kilberg, Jixiu Shan, Nan Su

Journal:

Trends in Endocrinology & Metabolism

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

34

Transcriptional regulation of the human asparagine synthetase gene by carbohydrate availability

BARBOSA-TESSMANN, Ione P., PINEDA, Van Leung, NICK, Harry S., SCHUSTER, Sheldon M., KILBERG, Michael S.

Journal:

Biochemical Journal

Year:

1999

Language:

english

File:

PDF, 285 KB

english, 1999

35

Asparagine Synthetase Is Highly Expressed at Baseline in the Pancreas Through Heightened PERK Signaling

Mukherjee, Amitava, Ahmed, Nayyar, Rose, Fateema, Ahmad, Abraheem N., Javed, Tanveer A., Wen, Li, Bottino, Rita, Xiao, Xiangwei, Kilberg, Michael S., Husain, Sohail Z.

Journal:

CMGH Cellular and Molecular Gastroenterology and Hepatology

Year:

2019

Language:

english

File:

PDF, 2.48 MB

english, 2019

36

Ontogeny of the neutral amino acid transporter SAT1/ATA1 in rat brain

Michael D. Weiss, Shag Derazi, Candace Rossignol, Helene Varoqui, Jeffrey D. Erickson, Michael S. Kilberg, Kevin J. Anderson

Journal:

Developmental Brain Research

Year:

2003

Language:

english

File:

PDF, 760 KB

english, 2003

37

Accumulation of α-Aminoisobutyric Acid by Rat Tissues after Whole-Body γ-Irradiation

Michael S. Kilberg and Otto W. Neuhaus

Journal:

Radiation Research

Year:

1975

Language:

english

File:

PDF, 982 KB

english, 1975

38

Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain

CHANG, Se-Ho, GARCIA, Jairo, MELENDEZ, J. Andres, KILBERG, Michael S., AGARWAL, Anupam

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 311 KB

english, 2003

39

Dysregulated insulin in pancreatic insufficient cystic fibrosis with post-prandial hypoglycemia

Kilberg, Marissa J., Sheikh, Saba, Stefanovski, Darko, Kubrak, Christina, De Leon, Diva D., Hadjiliadis, Denis, Rubenstein, Ronald C., Rickels, Michael R., Kelly, Andrea

Journal:

Journal of Cystic Fibrosis

Year:

2019

Language:

english

File:

PDF, 1.05 MB

english, 2019

40

Ontogeny and localization of the neutral amino acid transporter ASCT1 in rat brain

Michael D Weiss, Shag Derazi, Michael S Kilberg, Kevin J Anderson

Journal:

Developmental Brain Research

Year:

2001

Language:

english

File:

PDF, 1.12 MB

english, 2001

41

Hormonal regulation of hepatic amino acid transport

Michael S. Kilberg, Otto W. Neuhaus

Journal:

Journal of Cellular Biochemistry

Year:

1977

Language:

english

File:

PDF, 701 KB

english, 1977

42

HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes

Guimarães-Camboa, Nuno, Stowe, Jennifer, Aneas, Ivy, Sakabe, Noboru, Cattaneo, Paola, Henderson, Lindsay, Kilberg, Michael S., Johnson, Randall S., Chen, Ju, McCulloch, Andrew D., Nobrega, Marcelo A.,

Journal:

Developmental Cell

Year:

2015

Language:

english

File:

PDF, 5.89 MB

english, 2015

43

Analysis of the Mechanism of the pH-Dependent Shift in Substrate Affinity of ASCT1 Using Site-Directed Mutagenesis: Implications in the Pathophysiology of Hypoxic Ischemic Encephalopathy (HIE)

Weiss, Michael D, Aslanian, Ara M, Kilberg, Michael S

Journal:

Pediatric Research

Year:

1999

File:

PDF, 70 KB

1999

44

The Role of Stimulated Amino Acid Transport in Promoting Glycogenesis in the Irradiated Rat

Michael S. Kilberg and Otto W. Neuhaus

Journal:

Radiation Research

Year:

1976

Language:

english

File:

PDF, 1.23 MB

english, 1976

45

Recent Advances in Mammalian Amino Acid Transport

Kilberg, Michael S., Stevens, Bruce R., Novak, Donald A.

Journal:

Annual Review of Nutrition

Year:

1993

Language:

english

File:

PDF, 1.28 MB

english, 1993

46

Production of monospecific antibodies to a low-abundance hepatic membrane protein using nitrocellulose immobilized protein as antigen

Thomas C. Chiles, Thomas W. O'Brien, Michael S. Kilberg

Journal:

Analytical Biochemistry

Year:

1987

Language:

english

File:

PDF, 1.70 MB

english, 1987

47

Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation

Balasubramanian, Mukundh N., Shan, Jixiu, Kilberg, Michael S.

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

48

Amino-acid limitation induces transcription from the human C / EBP β gene via an enhancer activity located downstream of the protein coding sequence

Chen, Chin, Dudenhausen, Elizabeth, Chen, Hong, Pan, Yuan-Xiang, Gjymishka, Altin, Kilberg, Michael S.

Journal:

Biochemical Journal

Year:

2005

Language:

english

File:

PDF, 698 KB

english, 2005

49

Multiple adaptive mechanisms affect asparagine synthetase substrate availability in asparaginase-resistant MOLT-4 human leukaemia cells

ASLANIAN, Ara M., KILBERG, Michael S.

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 282 KB

english, 2001

50

Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells

Wortel, Inge M.N., van der Meer, Laurens T., Kilberg, Michael S., van Leeuwen, Frank N.

Journal:

Trends in Endocrinology & Metabolism

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

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